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404 ‒ Mental health beyond neurotransmitters: hormones in psychiatry, psychedelic therapies, & more

Peter Attia MD

In this episode, Peter sits down with Dr. Linus Abrams, a psychiatrist with nearly 35 years of clinical experience specializing in mood disorders and psychopharmacology, to explore how our understanding of mental health is evolving beyond the traditional neurotransmitter model. After decades in practice, Linus began questioning many of the assumptions underlying modern psychiatry, leading him to investigate how hormones, metabolism, inflammation, circadian biology, and the endocrine system shape mood and cognition. Together, Peter and Linus examine why psychiatric care should aim not only to r

Risks associated with thyroid supplements | Peter Attia, M.D.

This clip is from “Ask Me Anything” episode # 89 (Ep. # 308) of The Drive which was released on 9/21/26. In the full episode, we cover: -The two thyroid labs Peter checks on every patient, and the sit

Navigating subclinical hypothyroidism | Peter Attia, M.D.

This clip is from “Ask Me Anything” episode # 89 (Ep. # 308) of The Drive which was released on 9/21/26. In the full episode, we cover: -The two thyroid labs Peter checks on every patient, and the sit

Exercise for preserving cognitive function | Peter Attia, M.D.

This clip is from “Ask Me Anything” episode # 60 (Ep. # 306) of The Drive which was released on 6/17/24. In the full episode, we cover: -The relationship between lipids, CVD, and Alzheimer’s disease,

The phases of migraine | Brian Grosberg, M.D.

This clip is from episode # 406 of The Drive which was released on 8/31/26. In the full episode, we cover: -Why migraine is a neurologic disease rather than an ordinary headache, and why that distinct