Metabolic Vulnerability Index and mortality prediction | Jim Otvos, Ph.D.

This clip is from episode # 402 of The Drive which was released on 8/3/26. In the full episode, we cover: - Why LDL particle number can reveal cardiovascular risk that LDL cholesterol alone misses, and how the two can disagree -Why the popular idea that large, "fluffy" LDL particles are benign does not hold up, and the genetic condition that most clearly disproves it -How an NMR-derived score can detect insulin resistance and predict type 2 diabetes years before blood glucose begins to rise -Why GlycA, an NMR marker of chronic inflammation, offers a more stable signal than the hs-CRP test used